A formulation had been developed using a small scale laboratory press.
The product was to be transferred to a production site in a different location, using a full scale press.
Merlin carried out an assessment of the compaction properties of the formulation, comparing slow speed compression with a high speed simulated profile. This allowed the company to check for changes that may happen as dwell time shrinks.
Merlin was also able to use the proposed final capsule shape tooling as part of the assessment.
The results were used to predict the settings required in production and provide confidence in the choice of press and tablet shape.
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